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2'-deoxy-N-(naphthalen-1-ylmethyl)guanosine 5'-(dihydrogen phosphate)

Development stage
Unknown
Modality
Small Molecules
01

Overview

2'-deoxy-N-(naphthalen–1–ylmethyl)guanosine 5'-(dihydrogen phosphate) is a synthetic purine nucleoside monophosphate analog. It consists of a deoxyguanosine backbone with an N-substituted naphthalenemethyl group at the guanine base and a dihydrogen phosphate group at the 5' position. This compound belongs to the class of organic compounds known as purine 2'-deoxyribonucleoside monophosphates[1][4]. Its primary use is experimental; it has not been approved for clinical use or assigned any therapeutic indication. The mechanism of action is not established but may involve interactions typical of modified nucleotides such as incorporation into DNA or interference with nucleotide-processing enzymes.

Other names
(((2R,3S,5R)-3-hydroxy-5-(2-((naphthalen-1-ylmethyl)amino)-6-oxo-6,9-dihydro-1H-purin-9-yl)oxolan-2-yl)methoxy)phosphonic acid{[(2R,3S,5R)-3-hydroxy-5-{2-(naphthalen‑1‑ylmethyl)amino]-6‑oxo‑6,9‑dihydro‑1H-purin‑9‑yl}oxolan–2–yl]methoxy}phosphonic acid

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