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2'-O-acetylsalicortin
- Development stage
- Preclinical
- Modality
- Nucleic Acid-Directed Small Molecules → Small Molecules, Covalent Small Molecules → Small Molecules, Classical Binding Small Molecules → Small Molecules
01
Overview
2'-O-acetylsalicortin is a naturally occurring salicinoid glycoside isolated from Salix pseudolasiogyne (a willow species). It has been identified as a bioactive phytochemical with notable anti-adipogenic effects. In vitro studies show that it significantly suppresses lipid accumulation in differentiating adipocytes by inhibiting the expression of key lipogenic and adipogenic transcription factors at both mRNA and protein levels. This suggests potential utility in metabolic disease research, particularly for obesity-related conditions[5][1]. Its mechanism appears to involve modulation of gene expression related to fat cell development rather political direct enzyme inhibition.
- Other names
- 2'-Acetylsalicortin113270-30-7
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