2-(1H-imidazol-1-yl)-9-methoxy-8-(2-methoxyethoxy)benzo[c][2,7]naphthyridin-4-amine

This compound is an experimental small molecule belonging to the naphthyridine class. It has not been approved for any indication and is not in clinical development. The primary known activity is inhibition of the enzyme 3-phosphoinositide-dependent protein kinase 1 (PDK1), with an IC50 of approximately 70 nM. PDK1 plays a key role in cell signaling pathways involved in cell growth and survival; thus, inhibitors are being explored as potential anticancer agents. No developer or manufacturer information is available for this compound[1][4].

Other names

2-(imidazol-1-yl)-9-methoxy-8-(2-methoxyethoxy)benzo[c]2,7-naphthyridin-4-amineBenzo[c][2,7]naphthyridine, 9PDPK1_HUMAN