2-(3'-methoxyphenyl) benzimidazole-4-carboxamide

2-(3'-Methoxyphenyl) benzimidazole-4-carboxamide is a synthetic small molecule belonging to the phenylbenzimidazoles class. It is primarily recognized as an experimental compound with no current clinical or regulatory approval. The compound acts as an inhibitor of poly [ADP-ribose] polymerase 1 (PARP1), a key enzyme involved in DNA repair processes, and has demonstrated high binding affinity (Ki ~6 nM). While not approved for any medical indication, it serves as a valuable scaffold in medicinal chemistry research due to its potential anti-inflammatory, antimicrobial, antitumor, and antiviral activities. Its unique structure makes it useful for drug design and biological studies focused on PARP inhibition[1][2][4].

Other names

2-(3-methoxyphenyl)-1H-benzimidazole-4-carboxamide2-(3'-methoxyphenyl)-1-H-benzimidazole-4-carboxamideQ27094866Q-27094866Q 270948662-(3''-methoxyphenyl) benzimidazole-4-carboxamide2-(3-methoxyphenyl)-1H-benzoimidazole-4-carboxylic acid amide