Drug intelligence / Profile preview

2-(3-benzoylphenoxy)ethyl(hydroxy)formamide

Development stage
Preclinical
Modality
Small Molecules
01

Overview

2-(3-benzoylphenoxy)ethyl(hydroxy)formamide is a synthetic small molecule belonging to the benzophenone class of organic compounds. It has been investigated as an experimental agent and is primarily known as a peptide deformylase inhibitor. Peptide deformylase is an enzyme involved in bacterial protein maturation by removing the formyl group from nascent proteins; thus, inhibitors of this enzyme are explored for their potential antibacterial activity. The compound has not been approved for any clinical use and remains at the discovery or investigative stage[1][3][5].

Other names
N-[2-(3-benzoylphenoxy)ethyl]-N-hydroxyformamideFormamide, N-[2-(3-benzoylphenoxy)ethyl]-N-hydroxy-DEF_ECOLIDEF_HAEINDEF_STAAMDEF_STRR6
02

Targets

PDF (Peptide deformylase, mitochondrial)

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