2-(3-chloro-4-propoxyphenyl)acetic acid

2-(3-chloro-4-propoxyphenyl)acetic acid is a small molecule belonging to the phenol ether and phenylacetic acid derivative classes. It features a phenyl ring substituted with both chloro and propoxy groups and an acetic acid side chain. This compound has been investigated as a drug candidate primarily for its potential biological activities such as anti-inflammatory and analgesic effects. Its mechanism of action involves inhibition of prostaglandin G/H synthase 1 (PTGS1), also known as cyclooxygenase 1 (COX1), which is key in the biosynthesis of prostaglandins from arachidonic acid—a pathway central to inflammation and pain signaling[1][5][8]. The compound has mainly been used in research settings as a discovery agent or probe rather than an approved pharmaceutical.

Other names

(3-Chloro-4-propoxy-phenyl)-acetic acid(3-chloro-4-propoxyphenyl)acetic acid2-(3-chloro-4-propoxyphenyl)acetic acid23914-91-2