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2-(4-ethylpiperazin-1-yl)-4-(phenylamino)pyrazolo[1,5-a][1,3,5]triazine-8-carbonitrile
- Development stage
- Unknown
- Modality
- Small Molecules
01
Overview
A synthetic small molecule belonging to the class of n‑arylpiperazines. It is an experimental compound that acts as a potent inhibitor of casein kinase II subunit alpha (CK2α), a serine/threonine protein kinase involved in cell growth and survival pathways. The compound has been studied primarily in biochemical and structural biology research settings for its ability to bind CK2α with high affinity (Ki ≈ 24 nM). There are no approved clinical indications or marketed formulations for this molecule; it is used as a chemical probe or tool compound in kinase research[2][7][8].
- Other names
- 2-(4-Ethylpiperazin-1-yl)-4-(phenylamino)pyrazolo[1,5-a][1,3,5]triazine-8-carbonitrile2-(4-Ethylpiperazin-1-Yl)-4-(Phenylamino)Pyrazolo(1,5-A)(1,3,5)Triazine-8-carbonitrile4-Anilino-2-(4-Ethyl–Piperazin–Yl)Pyrazolo[1,5-a][1,3,5]Triazine–8–Carbonitrile
02
Targets
CK2 (Casein kinase II subunit alpha)
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