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2-(6-{[(3-chloro-2-methylphenyl)sulfonyl]amino}pyridin-2-yl)-N,N-diethylacetamide

Development stage
Unknown
Modality
Small Molecules
01

Overview

This compound is a synthetic small molecule belonging to the benzenesulfonamide class, with the molecular formula C18H22ClN3O3S and a molecular weight of approximately 395.9 g/mol. It is an experimental drug that has not been approved for any indication. The primary known mechanism of action is inhibition of the enzyme 11-beta-hydroxysteroid dehydrogenase 1 (11β-HSD1), which plays a role in glucocorticoid metabolism by converting inactive cortisone to active cortisol. Inhibition of this enzyme has been investigated as a potential therapeutic strategy for metabolic disorders such as type 2 diabetes and obesity, but there are no reported clinical trials or approvals for this compound[1][3][4].

Other names
2-(6-{[(3-Chloro-2-Methylphenyl)sulfonyl]amino}pyridin-2-Yl)-N,N-Diethylacetamide2-(6-(3-chloro-2-methylbenzenesulfonamido)pyridin-2-yl)-N,N-diethylacetamide2-[6-(3-chloro-2-methylbenzenesulfonamido)pyridin-2-yl]-N,N-diethylacetamide3G4
02

Targets

HSD11B1 (11-beta-hydroxysteroid dehydrogenase type 1)

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