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2-(cyclohexylmethylamino)-4-(phenylamino)pyrazolo[1,5-a][1,3,5]triazine-8-carbonitrile

Development stage
Unknown
Lead developer
Chugai Pharmaceutical
Modality
Small Molecules
01

Overview

This compound is a synthetic small molecule with the chemical formula C19H21N7 and a molecular weight of approximately 347.42 g/mol. It features a pyrazolotriazine core substituted with cyclohexylmethyl and phenylaniline groups. The compound is cataloged in several chemical and pharmacological databases (CHEMBL438303; DrugBank DB08353; BindingDB BDBM50214460). Its precise mechanism of action has not been fully elucidated or published in the available literature as of June 2025. It is classified as an experimental molecule and may have kinase inhibitory activity based on its structural class (pyrazolotriazines are often explored as kinase inhibitors), but no specific protein target or clinical indication has been confirmed in public sources[2][10]. There are no approved therapeutic uses or marketed products containing this compound.

Other names
2-(cyclohexylmethylamino)-4-(phenylamino)pyrazolo[1,5-a][1,3,5]triazine-8-carbonitrile2-[(cyclohexylmethyl)amino]-4-(phenylamino)pyrazolo[1,5-a][1,3,5]triazine-8-carbonitrile2-((cyclohexylmethyl)amino)-4-(phenylamino)pyrazolo(1,5-a)(1,3,5)triazine-8-carbonitrile4-anilino-2-[(cyclohexylmethyl)amino]pyrazolo[1,5-a][1,3,5]triazin-8-carbonitril
02

Targets

CK2 (Casein kinase II subunit alpha)

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