2-[(2,4-dichlorobenzoyl)amino]-5-(pyrimidin-2-yloxy)benzoic acid

A synthetic small molecule with the chemical formula C18H11Cl2N3O4 and a molecular weight of approximately 404.20 g/mol. It is an experimental compound that has not been approved for clinical use in any country and is not currently in clinical trials beyond preclinical or early research phases[1][3][6]. The structure features a benzoic acid core substituted with a dichlorobenzoyl group and a pyrimidinyloxy moiety[1][10]. It has been studied as a ligand for nuclear receptors such as retinoid X receptor alpha (RXRA), suggesting potential activity as an agonist or modulator of this receptor[1]. There are also references to its investigation in the context of peroxisome proliferator–activated receptors (PPARs), particularly PPARγ and PPARδ, but no evidence of advanced development or therapeutic application exists[8].

Other names

2-(2,4-dichlorobenzamido)-5-(pyrimidin-2-yloxy)benzoic acid5-(pyrimidin-2-yloxy)-2-benzoylaminobenzoic acidBenzoic acid, 2-[(2,4-dichlorobenzoyl)amino]-5-(pyrimidin-2-yloxy)