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2-[3-({Methyl[1-(2-Naphthoyl)Piperidin-4-Yl]Amino}Carbonyl)-2-Naphthyl]-1-(1-Naphthyl)-2-Oxoethylphosphonic Acid

Development stage
Unknown
Modality
Small Molecules
01

Overview

This compound is a synthetic small molecule with the chemical formula C40H35N2O6P and a molecular weight of approximately 670.7 Da. It belongs to the class of organic compounds known as stilbenes, which contain a 1,2-diphenylethylene moiety. The drug has been identified as an experimental agent and is not approved for clinical use in any country. Its primary mechanism of action is inhibition of Cathepsin G, a serine protease involved in inflammatory processes and tissue remodeling. There are no reported clinical trials or approved indications for this compound, and it remains at an early stage of research with no evidence of development beyond preclinical studies[1][4]. In silico studies have suggested potential antiviral activity against SARS-CoV‑2 main protease (3CLpro), but there are no published results from animal or human studies[6].

Other names
(1R)-2-(3-{methyl[1-(naphthalene-2-carbonyl)piperidin-4-yl]carbamoyl}naphthalen-2-yl)-1-(naphthalen-1-yl)-2-oxoethyl]phosphonic acid518062-14-1
02

Targets

CTSG (Cathepsin G)CMA1 (Chymase)

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