2-[3-(5-Mercapto-[1,3,4]thiadiazol-2yl)-ureido]-N-methyl-3-pentafluorophenyl-propionamide

This compound is a synthetic small molecule belonging to the class of phenylalanine derivatives. It features a pentafluorophenyl group and a thiadiazole ring with a mercapto substituent. The drug is known by the code name PNU-142372 and has been studied as an experimental agent. Its primary research context appears to be as an enzyme inhibitor—specifically as an inhibitor of matrix metalloproteinases (MMPs), which are enzymes involved in the breakdown of extracellular matrix components and have roles in cancer metastasis and other pathological processes. There are no approved indications or clinical trial data available for this compound[1][5][8].

Other names

2-[3-(5-Mercapto-[1,3,4]thiadiazol-2yl)-ureido]-N-methyl-3-pentafluorophenyl-propionamide(2S)-N-methyl-3-(pentafluorophenyl)-2-{[(5-sulfanyl-1,3,4-thiadiazol-2-yl)carbamoyl]amino}propanamide2,3,4,5,6-pentafluoro-N-methyl-Nalpha-[(5-sulfanyl-1,3,4-thiadiazol-2-yl)carbamoyl]-L-phenylalaninamide