2-[methyl-(5-geranyl-4-methyl-pent-3-enyl)-amino]-ethyl-diphosphate

2-[methyl-(5-geranyl-4-methyl-pent-3-enyl)-amino]-ethyl-diphosphate is an experimental small molecule and organophosphate compound. It is a synthetic analog of geranylgeranyl diphosphate, designed to interact with protein prenyltransferases such as farnesyltransferase and geranylgeranyltransferase type I. These enzymes catalyze the transfer of prenyl groups to target proteins, a key step in post-translational modification that affects protein localization and function. The compound has been studied primarily for its potential to modulate or inhibit these enzymes, which are implicated in oncogenic signaling pathways due to their role in modifying small GTPases like Ras and Rho family proteins[1][5][9]. There are no approved indications or marketed products containing this molecule.

Other names

3-azageranylgeranyl diphosphate