Drug intelligence / Profile preview

2-{(9as)-9a-[(1s)-1-Hydroxyethyl]-2,7-Dimethyl-9a,10-Dihydro-5h-Pyrimido[4,5-d][1,3]thiazolo[3,2-a]pyrimidin-8-yl}ethyl trihydrogen diphosphate

Development stage
Unknown
Modality
Small Molecules
01

Overview

This compound is a synthetic small molecule belonging to the class of organic pyrophosphates and is known as an experimental drug with no established clinical use in humans. It has been studied primarily as a ligand or inhibitor for biochemical research purposes rather than as a therapeutic agent. Its main identified biological target is acetolactate synthase (catabolic), specifically from the bacterium Klebsiella pneumoniae; however, its pharmacological action in humans remains unknown and it does not have an approved medical indication[2][6]. The compound's structure features a pyrimido-thiazolo-pyrimidine core with ethyl trihydrogen diphosphate substitution.

Other names
2-hydroxyethyl dihydrothiachrome diphosphate((hydroxy((2-((3S)-3-((1S)-1-hydroxyethyl)-6,12-dimethyl-4-thia-2,7,11,13-tetraazatricyclo(7.4.0.03)trideca-1(13),5,9,11-tetraen-5-yl)ethoxy))phosphoryl)oxy)phosphonic acid{[hydroxy({2-[ (3S ) - 3 - [ ( 1S ) - 1-hydroxyethyl ] -6 ,12-dimethyl -4-thia -2 ,7 ,11 ,13-tetraazatricyclo [7 .4 .0 .03 ]trideca -1 (13 ),5 ,9 ,11-tetraen -5-y l]ethoxy }) phosphoryl ] oxy } phosphonic acid
02

Targets

AHAS (Acetolactate synthase)

Beyond the preview

Go deeper on 2-{(9as)-9a-[(1s)-1-Hydroxyethyl]-2,7-Dimethyl-9a,10-Dihydro-5h-Pyrimido[4,5-d][1,3]thiazolo[3,2-a]pyrimidin-8-yl}ethyl trihydrogen diphosphate.

Explore the evidence, development activity, and competitive landscape with Gosset’s full data platform.

Clinical trials

Full profile access

Follow clinical development from study design and recruitment through results.

  • Trial phase
  • Status
  • Readouts

Indications & development

Full profile access

Explore development by indication, patient population, and geography.

  • Indications
  • Development status
  • Countries

Licensing & deals

Full profile access

Trace asset ownership, licensing agreements, and commercial partnerships.

  • Partners
  • Deal terms
  • Milestones

Patents & exclusivity

Full profile access

Explore the patent landscape and regulatory exclusivity around an asset.

  • Patents
  • Expiration dates
  • Exclusivity

Competitive landscape

Full profile access

Compare development programs by target, modality, and indication.

  • Competing assets
  • Targets
  • Development stage

Research & analysis

Full profile access

Connect source evidence and development news to your research questions.

  • Publications
  • News
  • Analysis

Bring the full picture into focus.

See how Gosset can support your research on 2-{(9as)-9a-[(1s)-1-Hydroxyethyl]-2,7-Dimethyl-9a,10-Dihydro-5h-Pyrimido[4,5-d][1,3]thiazolo[3,2-a]pyrimidin-8-yl}ethyl trihydrogen diphosphate.

Explore the full profile

Gosset Free

Get started with Gosset.

Enter your work email and we’ll be in touch with next steps.

Work email preferred.

Book a call