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2-amino-7-fluoro-5-oxo-5H-chromeno[2,3-b]pyridine-3-carboxamide
- Development stage
- Unknown
- Modality
- Small Molecules
01
Overview
A synthetic small molecule belonging to the chromeno[2,3-b]pyridine class. It is primarily known as an experimental compound and has been referenced as a DNA ligase inhibitor (DNA ligase-IN–2). The compound has not been approved for any therapeutic use and there are no reported clinical trials or indications. Its mechanism of action is presumed to involve inhibition of DNA ligases based on its code name and structural class. No developer or manufacturer information is available in public databases.[1][2][4]
- Other names
- 2-amino-7-fluoro-5-oxo-5H-chromeno[2,3-b]pyridine-3-carboxamide2-amino-7-fluoro-5-oxo-5H-chromeno(2,3-b)pyridine-3-carboxamide7-Fluoro-2-amino-5-oxo-[1]benzopyrano[2,3-b]pyridine–3-carboxamide
02
Targets
LigA (DNA ligase (NAD(+)-dependent))
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