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2012 trivalent influenza vaccine (Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo)

Development stage
Unknown
Lead developer
Instituto Butantan
Modality
Vaccines & Immunotherapeutics
Administration
Intradermal, Intramuscular
01

Overview

The 2012 trivalent influenza vaccine is a seasonal, inactivated viral vaccine designed to provide protection against three strains of the influenza virus. For the 2012 Southern Hemisphere season, the formulation typically included an A/California/7/2009 (H1N1)pdm09-like virus, an A/Perth/16/2009 (H3N2)-like virus, and a B/Brisbane/60/2008-like virus. This specific study conducted by the University of Sao Paulo evaluated the immunogenicity and safety of the vaccine when administered intradermally using a needle-free disposable-syringe jet injector (DSJI) compared to traditional intramuscular injection. The goal of such studies is often dose-sparing, where a smaller volume of vaccine delivered into the dermis (which is rich in antigen-presenting cells) can elicit an immune response comparable to a full dose delivered intramuscularly.

Other names
2012 seasonal influenza vaccinetrivalent inactivated influenza vaccine 2012
02

Targets

HA (Hemagglutinin)

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