Drug intelligence / Profile preview

3,20-pregnanedione

Development stage
Unknown
Modality
Small Molecules
01

Overview

**3,20-Pregnanedione** is a synthetic or naturally occurring steroid belonging to the class of gluco/mineralocorticoids and progestogens. It is a C21-steroid with oxo groups at positions 3 and 20 on the pregnane backbone. This compound exists as both a human and mouse metabolite and is structurally related to progesterone metabolites. While it has been studied as an experimental small molecule in research settings—particularly for its role in steroid metabolism—there are no approved therapeutic indications or clinical uses reported for this compound[1][2]. Its mechanism of action as a drug has not been established; however, related compounds can modulate neurosteroid activity.

Other names
5beta-pregnane-3,20-dione5β-pregnane-3,20-dionePregnane-3,20-dione, (5beta)-(5alpha,8alpha,10alpha,14beta,17alpha)-pregnane-3,20-dione

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