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3,4-dihydroxy-2-nitrophenyl)(phenyl)methanone
- Development stage
- Unknown
- Lead developer
- Bial
- Modality
- Small Molecules
01
Overview
(3,4-DIHYDROXY-2-NITROPHENYL)(PHENYL)METHANONE is a synthetic organic compound belonging to the benzophenone class. It features a ketone group attached to two phenyl rings, one of which is substituted with hydroxyl groups at positions 3 and 4 and a nitro group at position 2. The molecular formula is C13H9NO5 and its molecular weight is approximately 259.21 g/mol[1][2][6]. This compound has been studied as an experimental small molecule inhibitor of catechol O-methyltransferase (COMT), an enzyme involved in the metabolism of catecholamines such as dopamine[3]. There are no approved medical indications or marketed formulations for this compound; it remains primarily a research tool.
- Other names
- (3,4-dihydroxy-2-nitrophenyl)(phenyl)methanone3,4-dihydroxy-2-nitrobenzophenone
02
Targets
COMT (Catechol-O-methyltransferase)
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