3,4-dihydro-2'-deoxyuridine-5'-monophosphate

3,4-Dihydro‐2′‐deoxyuridine‐5′‐monophosphate is a synthetic or experimental nucleoside monophosphate analog belonging to the class of pentose phosphates and pyrimidine deoxyribonucleotides. It is structurally related to deoxyuridine monophosphate (dUMP), but features a saturated (dihydrouracil) base. The compound has not been approved for clinical use and is primarily used in research settings as a biochemical tool or substrate analog. Its mechanism of action would be expected to involve incorporation into DNA or interaction with enzymes involved in nucleotide metabolism; however specific pharmacological activity and indications are not established[1][2][4].

Other names

3,4-DIHYDRO-2'-DEOXYURIDINE-5'-MONOPHOSPHATE(((2R,3S,5R)-3-hydroxy-5-((4R)-4-hydroxy-2-oxo-1,2,3,4-tetrahydropyrimidin-1-yl)oxolan-2-yl)methoxy)phosphonic acid{[(2R,3S,5R)-3-hydroxy-5-(4-hydroxy–2–oxo–1,2,3,4-tetrahydropyrimidin–1–yl)oxolan–2–yl]methoxy}phosphonic acid(4R)-1-(2-deoxy‑5‑O‑phosphono‑beta‑D‑erythro-pentofuranosyl)-4-hydroxy‑3,4-dihydropyrimidin‑2(1H)-one