3-({2-[(2-amino-6-methylpyrimidin-4-yl)ethynyl]benzyl}amino)-1,3-oxazol-2(3H)-one

A synthetic small molecule belonging to the aminopyrimidine class. It is characterized by a pyrimidine core with an ethynyl linkage to a benzyl group and an oxazolone moiety. The compound has been identified as an experimental agent and is not approved for clinical use. Its primary known mechanism of action is inhibition of heat shock protein HSP 90-alpha (HSP90AA1), a molecular chaperone involved in the folding and stabilization of various client proteins implicated in cancer cell growth and survival. No approved indications or advanced clinical development have been reported for this molecule[7].

Other names

3-((2-((2-amino-6-methylpyrimidin-4-YL)ethynyl)benzyl)amino)-1,3-oxazol-2(3H)-one3-[({2-[2-(2-amino-6-methylpyrimidin-4-Yl)ethynyl]phenyl}methyl)amino]-2,3-dihydro-1,3-Oxazol–2-one