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3-({4-[(1E)-3-morpholin-4-yl-3-oxoprop-1-en-1-yl]-2,3-bis(trifluoromethyl)phenyl}sulfanyl)aniline

Development stage
Unknown
Modality
Small Molecules
01

Overview

This compound is a synthetic small molecule belonging to the class of cinnamic acid derivatives. It is known by the code name BQM and has been studied as an experimental inhibitor of integrin alpha-L (LFA‑1), a protein involved in leukocyte adhesion and migration. By targeting LFA‑1, this molecule may modulate immune cell trafficking and inflammatory responses. Its primary use has been in research settings to study integrin-ligand interactions; there are no approved therapeutic indications or clinical development programs reported for this compound[1][10].

Other names
(2E)-3-{4-[(3-Aminophenyl)sulfanyl]-2,3-bis(trifluoromethyl)phenyl}-1-(morpholin-4-yl)prop-2-en-1-one(2E)-3-{4-[(3-Aminophényl)sulfanyl]-2,3-bis(trifluorométhyl)phényl}-1-(4-morpholinyl)-2-propén-1-one(2E)-3-{4-[ ( 3 -aminophenyl ) sulfanyl ] - 2 , 3 -bis ( trifluoromethyl ) phenyl } - 1 -( morpholin - 4 - yl ) prop - 2-en - 1-oneBQM
02

Targets

ITGAL (Integrin alpha L (CD11a))

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