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3-(1H-indol-3-yl)-4-(1-{2-[(2S)-1-methylpyrrolidinyl]ethyl}-1H-indol-3-yl)-1H-pyrrole-2,5-dione
- Development stage
- Unknown
- Modality
- Small Molecules
01
Overview
This compound is a synthetic small molecule belonging to the class of n‑alkylindoles and maleimides. It features two indole moieties and a pyrrole‑dione core with an N‑alkylpyrrolidine substituent. The molecule has been studied as an experimental agent and is not approved for clinical use. According to DrugBank, it is associated with inhibition of protein kinases such as cAMP-dependent protein kinase catalytic subunit alpha (PKA) and possibly phosphoinositide-dependent protein kinase activity (PDPK1), suggesting potential utility as a kinase inhibitor in research settings[1][4][5]. No marketed indications or advanced clinical development are reported.
- Other names
- 3-(1H-indol-3-yl)-4-(1-{2-[(2R)-1-methylpyrrolidinyl]ethyl}-1H-indol-3-yl)-2,5-dihydro-1H-pyrrole-2,5-dioneDB07456DB-07456DB 07456LBFDERUQORUFIN-QGZVFWFLSA-N(R)-3-(1H-indol-3-yl)-4-(1-(2-(1-methylpyrrolidin-2-yl)ethyl)-1H-indol-3-yl)-1H-pyrrole-2,5-dione
02
Targets
PKA (Cyclic amp-dependent protein kinase)
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