Drug intelligence / Profile preview

3-(4'-bromothiophen-2'-yl)-7-hydroxycoumarin

Development stage
Preclinical
Modality
Small Molecules
Administration
Oral
01

Overview

3-(4'-bromothiophen-2'-yl)-7-hydroxycoumarin is a synthetic small molecule that combines a coumarin core, specifically a hydroxycoumarin, with a brominated thiophene substituent at the 3-position. The parent coumarin scaffold, especially 7-hydroxycoumarin (umbelliferone), is known for diverse pharmacological properties, including antioxidant and potential neuropharmacological activity. This derivative has been investigated for its *in vivo* effects, including modulation of locomotor activity, and is likely designed to enhance biological properties via the introduction of both a halogen and a heterocycle. Its mechanism of action is not fully characterized but presumed to interact with central nervous system targets through modulation of neurotransmitter pathways, based on related coumarin activity[6]. The drug does not have established brand, code, or alternative names in pharmaceutical registries.

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