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3-[isopropyl(4-methylbenzoyl)amino]-5-phenylthiophene-2-carboxylic acid
- Development stage
- Preclinical
- Modality
- Small Molecules
01
Overview
This compound is an amido thiophene derivative classified as a small molecule. It acts as an inhibitor of the Hepatitis C Virus (HCV) RNA polymerase, specifically targeting the viral enzyme responsible for RNA synthesis. Its primary mechanism is inhibition of EC 2.7.7.6 (RNA-directed RNA polymerase), which is essential for HCV replication. The drug has been studied experimentally but has not reached clinical approval or advanced clinical development stages[1][3][7].
- Other names
- 3-[Isopropyl(4-Methylbenzoyl)Amino]-5-Phenylthiophene-2-Carboxylic Acid3-{(1-methylethyl)[(4-methylphenyl)carbonyl]amino}-5-phenylthiophene-2-carboxylic acid3-(N-isopropyl4-methylbenzamido)-5-phenylthiophene-2-carboxylic acid3-[Isopropyl-(4-methyl-benzoyl)-amino]-5-phenyl-thiophene-2-carboxylic acid
02
Targets
NS5B (Hepatitis C virus non-structural protein 5B (NS5B) RNA-dependent RNA polymerase)
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