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3-{2,6,8-trioxo-9-[(2S,3R,4R)-2,3,4,5-tetrahydroxypentyl]-1,2,3,6,8,9-hexahydro-7H-purin-7-Yl}propyl dihydrogen phosphate

Development stage
Unknown
Modality
Metabolically Activated Prodrugs → Prodrugs/Conditional Activator Small Molecules → Small Molecules, Nucleic Acid-Directed Small Molecules → Small Molecules
01

Overview

This compound is a synthetic nucleotide analogue structurally related to xanthines and purine derivatives. It features a modified purine base (xanthine core), a tetrahydroxypentyl side chain (mimicking ribose), and a propyl dihydrogen phosphate group. Nucleotide analogues like this are often used as biochemical probes or in research settings to study enzyme interactions with nucleotides or as potential antiviral agents by mimicking natural nucleotides and interfering with viral replication processes. There is no evidence of clinical use or approval for therapeutic indications[1][9].

Other names
(3-(2,6,8-trioxo-9-((2S,3S,4R)-2,3,4,5-tetrahydroxypentyl)-1H-purin-7-yl)propoxy)phosphonic acid(3-{2,6,8-trioxo-9-[(2S,-3S,-4R)-2,-3,-4,-5-tetrahydroxypentyl]-1H-purin-7-y}propoxy)phosphonic acid

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