Drug intelligence / Profile preview

3-methoxy-4,5-methylenedioxyamphetamine

Development stage
Unknown
Modality
Small Molecules
Administration
Oral, Intranasal
01

Overview

MMDA (3-methoxy-4,5-methylenedioxyamphetamine) is a synthetic psychedelic and entactogen of the amphetamine class. It is structurally related to MDA and MDMA. MMDA produces effects such as euphoria, warmth, empathy, closed-eye visuals, muscle relaxation, and time distortion. Its mechanism of action has not been definitively established but is believed to involve agonism at the Serotonin receptor 2A (similar to other hallucinogenic amphetamines) and serotonin release by reversing the direction of the Serotonin transporter (like MDMA). MMDA has no approved medical use and is considered an illicit substance[1][5][8].

Other names
MMDA3-Methoxy-alpha-methyl-4,5-methylenedioxyphenethylamine3-Methoxy-methylenedioxyamphetamine
02

Targets

HTR2A (Serotonin receptor 5-HT2A)SERT (Sodium-dependent serotonin transporter)

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