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3-oxo-N-[(3S)-2-oxopyrrolidin-3-yl]dodecanamide

Development stage
Preclinical
Modality
Small Molecules
01

Overview

A synthetic small molecule belonging to the class of n-acyl-alpha amino acids and derivatives. It is structurally related to bacterial quorum sensing molecules known as N-acyl homoserine lactones (AHLs), specifically the Pseudomonas aeruginosa autoinducer N-(3‑oxododecanoyl) homoserine lactone. These compounds function as signaling molecules in bacterial communication (quorum sensing), regulating gene expression in response to cell population density. The compound itself is experimental and not approved for clinical use; it has been studied primarily for its role in chemical biology and microbiology research related to quorum sensing pathways[1][5][9].

Other names
3-OXO-N-[(3S)-2-OXOPYRROLIDIN-3-YL]DODECANAMIDE3-Oxo-N-(3S)-tetrahydro-2-oxo-3-furanyl-dodecanamideN-(3-Oxododecanoyl)-L-homoserine lactone L-enantiomer(S)-3-Oxo-N-(2‑oxotetrahydrofuran‑3‑yl)dodecanamideN-(3‑oxododecanoyl)‑L-homoserine lactone[5]
02

Targets

LuxR-type quorum sensing receptors

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