Drug intelligence / Profile preview

3BP (211At)

Development stage
Preclinical
Lead developer
3B Pharmaceuticals
Modality
Antibody-Radionuclide Conjugates → Antibody Conjugates → Antibody-Based Therapeutics, Peptides
Administration
Intravenous
01

Overview

3BP (211At) (also known as 3BP-TBD) is a preclinical-stage targeted alpha therapy (TAT) being co-developed by TetraKit Technologies and 3B Pharmaceuticals (3BP) under a strategic collaboration announced in April 2025. The candidate is a novel peptide radiopharmaceutical designed for oncology indications. It utilizes TetraKit's proprietary click chemistry-based radiolabeling platform to conjugate a cancer-targeting peptide discovered by 3B Pharmaceuticals with the alpha-emitting radionuclide astatine-211 (211At). This approach aims to deliver highly localized, high-energy alpha radiation directly to tumor cells while minimizing damage to surrounding healthy tissues. The specific biological target and oncology indications remain undisclosed.

Other names
3BP

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