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3Mixtatin (Tabriz University of Medical Sciences)
- Development stage
- Preclinical
- Lead developer
- Tabriz University of Medical Sciences
- Modality
- Small Molecules
- Administration
- Topical
01
Overview
**3Mixtatin** is an investigational, locally compounded endodontic paste used in pulp therapy of primary molars. In the formulation used in the Cairo University clinical-trial context, it combines the antibacterial agents **cefixime, ciprofloxacin, and metronidazole** with **simvastatin**. The antibiotics are intended to sterilize infected pulp and root-canal tissues, while simvastatin is included for anti-inflammatory and putative bioinductive or hard-tissue regenerative effects. It is applied directly to the pulp or root-canal space during procedures such as pulpotomy or lesion sterilization and tissue repair for pediatric primary teeth.
- Brand names
- 3Mixtatin
- Other names
- 3-Mix-tatin3MIX-TATIN3Mixstatin
02
Targets
HMGCR (3-hydroxy-3-methylglutaryl-coenzyme A reductase)NeuraminidaseTopo IV (Bacterial Topoisomerase IV)Bacterial RibosomeDNA gyrase
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