4-(1,3-benzodioxol-5-yl)-5-(5-ethyl-2,4-dihydroxyphenyl)-2h-pyrazole-3-carboxylic acid

This compound is a synthetic small molecule with the chemical formula C19H16N2O6 and a molecular weight of 368.34 g/mol[6][7][9]. It is primarily used as an experimental or research tool and does not have any approved medical indications. The compound has been identified as a ligand for heat shock protein HSP 90-alpha (HSP90AA1), with reported binding affinity (Kd) of approximately 680 nM[6]. HSP90 is a molecular chaperone involved in the folding and stabilization of many proteins required for tumor growth; thus, inhibitors of HSP90 are being explored as potential antineoplastic agents. However, there is no evidence that this molecule has advanced beyond preclinical or early experimental stages.

Other names

4-(2h-1,3-benzodioxol-5-yl)-3-(5-ethyl-2,4-dihydroxyphenyl)-1h-pyrazole-5-carboxylic acidCHEMBL178130CHEMBL-178130CHEMBL 178130374699-77-1