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4-(2-hydroxybenzylamino)-N-(3-(4-fluorophenoxy)phenyl)piperidine-1-sulfonamide
- Development stage
- Unknown
- Modality
- Small Molecules
01
Overview
4-(2-hydroxybenzylamino)-N-(3-(4-fluorophenoxy)phenyl)piperidine-1-sulfonamide is an experimental small molecule compound belonging to the class of diphenylethers. It has been studied as a potential inhibitor of mitogen-activated protein kinase 14 (MAPK14, also known as p38 alpha MAP kinase), with reported in vitro activity (IC50 ~6000 nM). The compound's primary research use is in biochemical and structural studies related to kinase inhibition, but it does not have any approved therapeutic indications or established clinical development programs[1][6].
- Other names
- N-[3-(4-fluorophenoxy)phenyl]-4-{[(2-hydroxyphenyl)methyl]amino}piperidine-1-sulfonamideN-[3-(4-fluorophenoxy)phenyl]-4-{[(2-hydroxybenzyl)amino]}piperidine-1-sulfonamide
02
Targets
MAPK14 (p38 mitogen-activated protein kinase alpha)
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