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4-(4-hydroxyphenyl)-1-naphthaldehyde oxime

Development stage
Unknown
Modality
Small Molecules
01

Overview

**Description:** 4-(4-hydroxyphenyl)-1-naphthaldehyde oxime is a synthetic small molecule with the molecular formula C17H13NO2 and a molecular weight of approximately 263.29 g/mol[1][2][5]. It features both a naphthalene moiety and an oxime functional group, as well as a para-hydroxylated phenyl ring. This compound is primarily studied for its interaction with estrogen receptors, particularly estrogen receptor beta, where it acts as an inhibitor[5][7]. Its binding affinity and selectivity for estrogen receptor beta have been demonstrated in biochemical assays, suggesting potential utility in modulating diseases influenced by estrogen signaling[5]. However, it has not been approved for any clinical use and remains classified as experimental[4].

Other names
4-(4-hydroxyphenyl)-1-naphthaldehyde oxime799765-95-04-(4-Hydroxyphenyl)-1-naphthalenecarboxaldehyde oxime4-(4-(Hydroxyiminomethyl)naphthalen-1-yl)phenol4-{4-[(E)-(hydroxyimino)methyl]naphthalen-1-yl}phenol
02

Targets

ESR2 (ERβ)

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