4-(5,11-dioxo-5H-indeno[1,2-c]isoquinolin-6(11H)-yl)butanoate

4-(5,11-dioxo-5H-indeno[1,2-c]isoquinolin-6(11H)-yl)butanoate is a synthetic small molecule belonging to the indenoisoquinoline class of compounds. Indenoisoquinolines are aromatic polycyclic molecules that have been investigated for their potential as topoisomerase I inhibitors and possible antineoplastic (anticancer) agents. This compound is considered experimental and has not been approved for clinical use. Its mechanism of action is presumed to involve inhibition of DNA topoisomerase I by stabilizing the cleavable complex between DNA and the enzyme during replication or transcription processes. The compound has primarily been studied in preclinical settings as a chemical probe or lead structure for further drug development within oncology research.[1][2][4]

Other names

4-(5,11-DIOXO-5H-INDENO[1,2-C]ISOQUINOLIN-6(11H)-YL)BUTANOATE4-(5,11-dioxoindeno[1,2-c]isoquinolin-6-yl)butanoic acidindeno[1,2-c]isoquinoline-6-butyric acid