4-(6-hydroxy-1H-indazol-3-yl)benzene-1,3-diol

4-(6-hydroxy-1H-indazol-3-yL)benzene‑1,3‑diol is a synthetic small molecule belonging to the class of phenylpyrazoles and azole derivatives[1][4]. It has been studied as a ligand for the estrogen receptor and is known to bind with high affinity (IC50 ~48 nM)[1][9]. Structural studies have shown it can modulate estrogen receptor conformation in ways that may selectively influence gene expression related to inflammation[9]. Its primary use is experimental; it has not been approved for clinical use or assigned therapeutic indications. The compound is referenced in chemical databases such as ChEMBL (CHEMBL223026), PubChem (14086997), and others[7].

Other names

4-(6-hydroxy-1H-indazol-3-yl)benzene-1,3-diol4-(6-Hydroxyindazolyl)-resorcinol