Drug intelligence / Profile preview

4-(hydroxymethyl)benzamidine

Development stage
Unknown
Modality
Small Molecules
01

Overview

4-(Hydroxymethyl)benzamidine is a synthetic small molecule belonging to the class of benzyl alcohols and amidines. It features a benzene ring substituted with both a hydroxymethyl group and an amidine group in the para position. The compound is primarily used as an experimental tool in biochemical research rather than as an approved pharmaceutical agent. Its structure suggests potential activity as a serine protease inhibitor—similar to its parent compound benzamidine—but there are no approved medical indications or clinical trial data supporting therapeutic use for any disease[1][2][3][7]. The mechanism of action is presumed to involve reversible inhibition of serine proteases by binding competitively at their active sites.

Other names
4-(Hydroxymethyl)Benzamidine4-(hydroxymethyl)benzenecarboximidamide68382-17-2E678E6SN42E-678E6SN42E 678E6SN42DTXSID30332280DTXSID-30332280DTXSID 30332280DTXCID20283373DTXCID-20283373DTXCID 20283373
02

Targets

F2 (Thrombin)

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