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4-(Isopropylamino)diphenylamine, also known as IPPD, is a small molecule chemical compound primarily used as an antiozonant in rubber manufacturing, especially for tires. In the medical context, it is approved for use in allergenic epicutaneous patch tests to aid in the diagnosis of allergic contact dermatitis (ACD) in individuals aged six years and older. It is a known allergen and can cause sensitivity reactions detectable by clinical patch testing. The mechanism of action related to its diagnostic use has not been specified[1][3].
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