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4-chloro-N'-[(1E)-(3,5-dibromo-2,4-dihydroxyphenyl)methylidene]benzohydrazide
- Development stage
- Unknown
- Modality
- Small Molecules
01
Overview
4-chloro-N'-[(1E)-(3,5-dibromo-2,4-dihydroxyphenyl)methylidene]benzohydrazide is an experimental small molecule belonging to the class of organic compounds known as 4-halobenzoic acids and derivatives. It features a benzohydrazide backbone substituted with a chloro group and a dibromodihydroxyphenyl moiety via a hydrazone linkage. The compound has been studied for its potential biological activity and is reported to act as an inhibitor of the bacterial enzyme 3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ. This enzyme plays a key role in unsaturated fatty acid biosynthesis in bacteria[1][2][6]. The compound's mechanism suggests possible antibacterial properties by targeting lipid biosynthesis pathways.
- Other names
- 4-chloro-N'-[(1E)-(3,5-dibromo-2,4-dihydroxyphenyl)methylidene]benzohydrazide
02
Targets
FabZ (3-hydroxyacyl-ACP dehydratase FabZ)
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