Drug intelligence / Profile preview

5,5-dimethyl-2-morpholin-4-yl-5,6-dihydro-1,3-benzothiazol-7(4H)-one

Development stage
Unknown
Modality
Small Molecules
01

Overview

A synthetic small molecule belonging to the class of dialkylarylamines and thiazolyl morpholine derivatives. It is listed as an experimental compound in pharmaceutical databases and has been identified as a potent and selective inhibitor of phosphatidylinositol 4,5-bisphosphate 3‑kinase catalytic subunit gamma isoform (PI3Kγ). The compound has not been approved for any indication and is primarily used in research settings. Its mechanism involves inhibition of PI3Kγ with an IC50 value reported at approximately 1660 nM[2][3]. No clinical trials or therapeutic indications are currently registered.

Other names
5,5-dimethyl-2-(morpholin-4-yl)-4,5,6,7-tetrahydro-1,3-benzothiazol-7-one15091-04-05,5-dimethyl-2-morpholin-4-yl-4,6-dihydro-1,3-benzothiazol-7-one2-(morpholin-4‑yl)-5,5‑dimethyl‑4,5,6,7‑tetrahydrobenzothiazol‑7-one
02

Targets

PIK3CG (Phosphatidylinositol 4,5-bisphosphate 3-kinase gamma)

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