5,6-diphenyl-N-(2-piperazin-1-ylethyl)furo[2,3-d]pyrimidin-4-amine

5,6-diphenyl-N-(2-piperazin-1-ylethyl)furo[2,3-d]pyrimidin-4-amine is an experimental small molecule belonging to the furopyrimidine and N‑alkylpiperazine chemical classes. It has been studied as a selective inhibitor of tyrosine-protein kinase Lck (Lck), a member of the Src family kinases involved in T-cell receptor signaling. The compound exhibits potent inhibitory activity against Lck with an IC50 of approximately 81 nM. There are no approved indications or clinical trials for this compound as of now; it remains at the preclinical or early research stage and is not approved for any therapeutic use[1][2][7].

Other names

5,6-DIPHENYL-N-(2-PIPERAZIN-1-YLETHYL)FURO(2,3-D)PYRIMIDIN-4-AMINE5,6-diphenyl-N-[2-(1-piperazinyl)ethyl]furo[2,3-d]pyrimidin-4-amino