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Drug intelligence / Profile preview
5-bromo-2-{[(4-chlorophenyl)sulfonyl]amino}benzoic acid
- Development stage
- Unknown
- Modality
- Small Molecules
01
Overview
A synthetic small molecule belonging to the sulfanilide class of organic compounds. It is characterized by a benzoic acid core substituted with a bromo group and a (4-chlorophenyl)sulfonamide moiety. The compound acts as an inhibitor of methionine aminopeptidase 2 (MetAP2), an enzyme involved in protein processing and angiogenesis. While it has been studied experimentally for its biochemical properties and potential biological activity related to MetAP2 inhibition—an approach explored in antiangiogenic cancer therapy—it is not approved for clinical use or any therapeutic indication[1][2][6].
- Other names
- 5-bromo-2-(4-chlorobenzenesulfonamido)benzoic acid5-bromo-2-(4-chlorophenylsulfonamido)benzoic acid5-BROMO-2-{[(4-chlorophenyl)sulfonyl]amino}benzoic acid5-bromo-2-[[(4-chlorobenzene)sulfonamido]benzoic acidBenzoic acid 5-bromo-2-[[(4-chlorophenyl)sulfonyl]amino]-
02
Targets
METAP2 (Methionine aminopeptidase 2)
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