5-fluoro-1-[4-(4-phenyl-3,6-dihydropyridin-1(2h)-yl)butyl]quinazoline-2,4(1h,3h)-dione

This compound is an experimental small molecule with the chemical formula C23H24FN3O2 and a molecular weight of approximately 393.46 g/mol[1][3]. It is a quinazolinone derivative featuring a fluorine atom at position five and a butyl-linked phenyl dihydropyridine moiety. The compound has been referenced in chemical databases as FRQ and PD005033[7]. There are no approved medical indications or clinical trials associated with this drug as of now[4]. Mechanistically, it has been identified in structural studies as binding to poly [ADP-ribose] polymerase enzymes (PARP), specifically PARP1 and PARP2[3], suggesting potential activity as a PARP inhibitor.

Other names

5-fluoro-1-[4-(4-phenyl,3,6-dihydropyridin-1(2H)-YL)butyl]quinazoline-2,4(1H,3H)-dione5-fluoro-1-[4-(4-phényl,-3,6-dihydro,-1(2H)-pyridinyl)butyl]-2,4(1H,3H)-quinazolinedione5-fluor-1-[4-(4-pheny,l3,6-dihydro,-2H-pyridin,-1-y,l)buty,l]-3,H-quina,zoline-,2,,4-di,on,equinazolidinone analogue 2b