5-methoxy-1,2-dimethyl-3-(phenoxymethyl)indole-4,7-dione

5-Methoxy-1,2-Dimethyl-3-(Phenoxymethyl)Indole-4,7-Dione is a synthetic small molecule belonging to the indole family. It has a molecular formula of C18H17NO4 and a molecular weight of approximately 311.3 g/mol[1][2][3][5]. This compound is classified as an indolequinone derivative and is primarily studied as an experimental tool compound rather than for therapeutic use. Notably, it has been used in biochemical research as a mechanism-based inhibitor of NAD(P)H:quinone oxidoreductase 1 (NQO1), an enzyme involved in cellular redox regulation[4][9]. The inhibition occurs via covalent modification after metabolic activation by NQO1. There are no approved medical indications or clinical trials for this compound; its primary application remains in laboratory studies investigating NQO1 function.

Other names

5-methoxy-1,2-dimethyl-3-(phenoxymethyl)-4,7-dihydro-1H-indole-4,7-dione5-methoxy-1,2-dimethyl-3-(phenoxymethyl)-1H-indole-4,7-dione210578-26-0