5-methyl-2-[(phenylsulfonyl)amino]benzoic acid

5-methyl-2-[(phenylsulfonyl)amino]benzoic acid is a synthetic small molecule belonging to the sulfanilide class of organic compounds, characterized by a benzoic acid core substituted with a methyl group and a phenylsulfonamide moiety. It has been identified as an experimental inhibitor of methionine aminopeptidase 2 (MetAP2), an enzyme involved in the removal of N-terminal methionine residues from nascent proteins. Inhibition of MetAP2 has been explored for potential antiangiogenic and anticancer effects, though this compound itself is not approved for any clinical use and remains at the experimental stage[1][2][4].

Other names

2-benzenesulfonamido-5-methylbenzoic acid2-(benzenesulfonamido)-5-methylbenzoic acid5-methyl-2-(phenylsulfonamido)benzoic acid