Drug intelligence / Profile preview

6-(3-bromo-2-naphthyl)-1,3,5-triazine-2,4-diamine

Development stage
Unknown
Modality
Small Molecules
01

Overview

6-(3-bromo-2-naphthyl)-1,3,5-triazine-2,4-diamine is a synthetic small molecule belonging to the triazine class and naphthalene derivatives. It is primarily studied as an experimental compound and has been identified as an "inhibitor of heat shock protein HSP90 (both alpha and beta isoforms). HSP90 is a molecular chaperone involved in the folding and stabilization of many proteins required for tumor growth; thus inhibition of HSP90 can disrupt multiple signaling pathways in cancer cells. This compound has not been approved for clinical use but serves as a tool molecule in research settings focused on cancer biology and drug discovery[1][8][3].

Other names
6-(3-bromonaphthalen-2-yl)-1,3,5-triazine-2,4-diamine1,3,5-Triazine-2,4-diamine, 6-(3-bromo-2-naphthalenyl)-HSP90 Inhibitor 1HSP-90 Inhibitor 1HSP 90 Inhibitor 1hsp90_125
02

Targets

HSP90AB1 (Heat shock protein HSP 90-beta)HSP90AA1 (Heat shock protein HSP90-alpha)

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