6-CHLORO-3-(3-METHYLISOXAZOL-5-YL)-4-PHENYLQUINOLIN-2(1H)-ONE

This compound is a synthetic small molecule belonging to the phenylquinoline class of organic compounds. It has the molecular formula C₁₉H₁₃ClN₂O₂ and a molecular weight of approximately 336.77 g/mol[1][2][3]. The compound is experimental and not approved for clinical use in any country[1]. Its primary known biological activity is as an inhibitor of macrophage colony-stimulating factor 1 receptor (CSF1R), with an IC50 value of approximately 140 nM[1]. CSF1R inhibition may have potential applications in modulating immune responses or treating diseases involving macrophage proliferation or function; however, there are no reported clinical trials or approved indications for this molecule as of now[1].

Other names

6-chloro-3-(3-methylisoxazol-5-yl)-4-phenylquinolin-2(1h)-one6-chloro-3-(3-methyl-1,2-oxazol-5-yl)-4-phenyl-1,2-dihydroquinolin-2-one