6-grass pollen mixture extract + dermatophagoides pteronyssinus extract + birch pollen extract + mugwort pollen extract

This is a **combination allergen extract** used in allergen immunotherapy for the treatment or prevention of allergic rhinitis and/or conjunctivitis in patients sensitized to grass pollens (6-grass blend), house dust mite (dermatophagoides pteronyssinus), birch pollen, and mugwort pollen. Allergen immunotherapy functions by administering controlled amounts of allergens over time, aiming to induce immune tolerance and reduce allergic symptoms. Clinical studies confirm efficacy and safety for individual components such as standardized grass pollen mixtures[7], birch pollen extract[2][4][6], and house dust mite extract in sublingual and injectable immunotherapy for IgE-mediated allergic conditions. Mechanistically, the treatment works by modulating the immune response to decrease allergen-specific IgE and increase blocking IgG4 antibody levels, reducing symptom severity and medication need during relevant pollen seasons[7][4][2][6]. The combination is generally administered via sublingual or subcutaneous route, often following standardized protocols.