64Cu-DOTA-TATE (Univ. of Pittsburgh)

64Cu-DOTA-TATE (Univ. of Pittsburgh): sourced facts only. name: "We explored targeting the SSTR2 receptor using Octreotate radiolabeled with copper-64 ( 64 Cu-DOTA-TATE) and found that specific uptake of 64 Cu-DOTA-TATE was highest in D341 cells with a mean and standard deviation of 39,272 +/- 826 counts as compared to 280 +/- 73 counts in D341 cells blocked with excess peptide." [DOI:10.1158/1535-7163.TARG-25-C089]; target: "We explored targeting the SSTR2 receptor using Octreotate radiolabeled with copper-64 ( 64 Cu-DOTA-TATE) and found that specific uptake of 64 Cu-DOTA-TATE was highest in D341 cells with a mean and standard deviation of 39,272 +/- 826 counts as compared to 280 +/- 73 counts in D341 cells blocked with excess peptide." [DOI:10.1158/1535-7163.TARG-25-C089]; developer: "University of Pittsburgh, Pittsburgh, PA." [DOI:10.1158/1535-7163.TARG-25-C089]; modality: "We hypothesize that targeted radiopharmaceutical therapy will result in higher uptake within the tumor while sparing the surrounding healthy brain." [DOI:10.1158/1535-7163.TARG-25-C089]; stage: "The mean standardized uptake value (SUV) following PET imaging of a mouse with an intracranial tumor was 0.31 in the tumor and 0.08 in the healthy brain at 1 hour, and 0.17 in the tumor and 0.08 in the healthy brain at 24 hours post-injection of 64 Cu-DOTA-TATE." [DOI:10.1158/1535-7163.TARG-25-C089]