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68Ga-P3 + 18F-P3

Development stage
Preclinical
Modality
Small Molecules, Antibody-Radionuclide Conjugates → Antibody Conjugates → Antibody-Based Therapeutics, Peptides
Administration
Intravenous
01

Overview

68Ga-P3 + 18F-P3 is a combination of two radiopharmaceutical imaging agents, each consisting of the PSMA-targeting ligand P3 labeled with a different positron-emitting radioisotope—gallium-68 (68Ga) and fluorine-18 (18F). Both components are designed for use in positron emission tomography (PET) imaging to detect prostate-specific membrane antigen (PSMA)-expressing cells, most notably in prostate cancer. The P3 ligand binds specifically to PSMA on the surface of prostate cancer cells; when labeled with either gallium-68 or fluorine-18, it enables high-sensitivity PET imaging for diagnosis and staging. This dual-tracer approach may be used to compare or complement the pharmacokinetics and imaging characteristics of each isotope-labeled agent in clinical research or advanced diagnostic protocols[1][7].

02

Targets

PSMA (Prostate-specific membrane antigen)

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