7-alpha-D-Ribofuranosyl-2-aminopurine-5'-phosphate

7-alpha-D-Ribofuranosyl-2-aminopurine-5'-phosphate is a synthetic nucleotide analog and small molecule with the chemical formula C10H14N5O7P and a molecular weight of approximately 347.22 g/mol[1][2][3][8]. It is not an approved pharmaceutical drug but has been studied experimentally, particularly as a substrate or product in enzymatic reactions related to cobalamin (vitamin B12) biosynthesis. Specifically, it is involved in the activity of nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase (CobT), which catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide and 5,6-dimethylbenzimidazole[1][6]. Additionally, computational studies have suggested that this compound may act as an inhibitor of UBE2C (ubiquitin-conjugating enzyme E2C), indicating potential research interest in oncology or cell cycle regulation[5]. However, there are no clinical trials or approved indications for this compound.

Other names

7RA7-α-D-Ribofuranosyl-2-aminopurine-5'-phosphate