Drug intelligence / Profile preview

8-(1,3-benzodioxol-5-ylmethyl)-9-butyl-2-fluoropurin-6-amine

Development stage
Unknown
Lead developer
Myrexis
Modality
Small Molecules
01

Overview

This compound is a synthetic small molecule belonging to the class of organic compounds known as 6‑aminopurines. It features a purine core substituted at position 6 with an amino group and at positions 8 and 9 with a benzodioxole-methyl and butyl group respectively; it also contains a fluorine atom at position 2. The compound has been studied experimentally as an inhibitor of heat shock protein HSP90 (heat shock protein HSP90-alpha), which is involved in protein folding and stabilization under stress conditions. There are no approved indications or clinical uses for this molecule; it remains an experimental research tool in molecular chaperone biology.[1][2][10]

Other names
8-Benzo[1,3]Dioxol-,5-Ylmethyl-9-butyl-2-fluoro-9H-purin-6-ylamine8-(2H-1,3-benzodioxol-5-ylmethyl)-9-butyl-2-fluoro-purin-6-amino[10]8-Benzo(1,3)Dioxol-,5-Ylmethyl–9–Butyl–2–Fluoro–9h-Purin–6-Ylamine[1][2]
02

Targets

HSP90AA1 (Heat shock protein HSP90-alpha)

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